HWI News
20 years of crystal hits
A paper entitled 20 years of crystal hits: progress and promise in ultrahigh-throughput crystallization screening by Miranda L. Lynch, M. Elizabeth Snell, Stephen A. Potter, Edward H. Snell, Sarah E. J. Bowman has been published in Acta Cryst D. Volume 79, pages...
Drs Edward Snell and Stephan Ginell elected as American Crystallographic Association Fellows
Congratulations to Edward Snell and Stephan Ginell on being elected as American Crystallographic Association Fellows! The American Crystallographic Association – the Structural Science Society - established the Fellows distinction to recognize a high level of...
HWI staff in Chicago help Pfizer create an effective COVID-19 treatment
Our team at the Advanced Photon Source have helped Pfizer create a COVID-19 treatment. The new drug candidate, Paxlovid, significantly reduced hospitalization and death in adult patients, according to Pfizer, and will be submitted for an emergency use authorization in...
Studying radiation damage in biological systems – New tools and new knowledge
X-ray-based techniques are a powerful tool in structural biology but the radiation-induced chemistry that results can be detrimental and may mask an accurate structural understanding. Therapeutic radiation is used for cancer treatment and understanding the biological...
Hauptman-Woodward Medical Research Institute Welcomes Six New Board Members
The Hauptman-Woodward Medical Research Institute (HWI), an international leader in structural biology located on the Buffalo Niagara Medical Campus, announced that six new members were recently elected to three-year terms on the organization’s Board of Directors. The...
Hauptman-Woodward Medical Research Institute Crystallization Center Awarded Major Grant by National Institutes of Health
Five-year award brings prestige, jobs, investment to Western New York The Hauptman-Woodward Medical Research Institute (HWI), an international leader in structural biology located on the Buffalo Niagara Medical Campus, has been awarded a grant totaling nearly $5...
Structural biology at the center of COVID-19 scientific efforts
The COVID-19 pandemic has impacted almost every aspect of our lives in the past year and continues to do so. In March, at the one-year mark of the World Health Organization declaration that COVID-19 is a pandemic, researchers at HWI – Drs. Miranda Lynch, Edward Snell...
Nobel Laureate Dr. Joachim Frank to Give Inaugural Lecture for New Cryo-Electron Microscopy Center at Hauptman-Woodward
State-of-the-art research center to be launched in February The Hauptman-Woodward Medical Research Institute (HWI), an international leader in structural biology located on the Buffalo Niagara Medical Campus, will host Nobel Laureate Dr. Joachim Frank for a virtual...
Engineering high-resolution insight from a low-resolution technique
A significant problem in biological X-ray crystallography is the radiation chemistry caused by the incident X-ray beam. This produces both global and site-specific damage. Site-specific damage can misdirect the biological interpretation of the structural models...