At Hauptman-Woodward we learn how diseases originate
and how to cure them. CURES BEGIN HERE.

Science

AN EXAMPLE OF STRUCTURAL BIOLOGY

AN EXAMPLE OF STRUCTURAL BIOLOGY
Above is Cyclooxygenase, an enzyme we study. It is associated with the causes and symptoms of diseases, like inflammation, cardiovascular disease, and cancer Medications like aspirin and ibuprofen target this enzyme and above you will see how ibuprofen fits in it to stop a pain signal. This 3D picture of how a drug works is a result of structural biology. It sets the foundation for the development of new and more effective drugs.​

At Hauptman-Woodward, our research develops an understanding of how living cells function. With this knowledge, we learn how diseases originate and how to cure them or alleviate their symptoms.

For more than half a century, Hauptman-Woodward Medical Research Institute scientists have been committed to finding the fundamental causes of many diseases. For example, cancer is being attacked by identifying new classes of antitumor agents including new inhibitors for hormone-dependent breast tumors. Other projects include finding new ways to fight opportunistic infections in AIDS patients, combating inflammation in arthritis and cardiovascular disease, and preventing bronchial infections in cystic fibrosis patients.

Hauptman-Woodward Medical Research Institute scientists use a methodology known as structural biology, which allows them to create three-dimensional models of the molecules that build up our cells. The results of their investigations provide many insights into how these molecular machines work, including the starting points for better drug design. In addition, other research on-going, the Institute seeks to make technological improvements in the process of creating these three-dimensional molecular models – improvements that will enhance the productivity of scientists all over the world.

 

We thrive on CURE•OSITY.