The Crystallization Center at HWI
NEWS
Drs. Que and Gewirth Publish in Proteins
Drs. Nanette Que and Dan Gewirth at the Hauptman-Woodward Medical Research Institute have published a paper in Proteins: Structure, Function, and Bioinformatics analyzing how drugs bind selectively to a protein that is an emerging therapeutic target for cancer and other diseases.
NEWS
Department of Energy three-year grant for AI-assisted biomedical research
The U.S. Department of Energy has awarded $1.5 million to a joint Hauptman-Woodward Medical Research Institute and University at Buffalo research project that will use artificial intelligence to study how cells and molecules respond to low doses of radiation. Dr. Edward Snell, Chief Scientific Officer at Hauptman-Woodward Medical Research Institute, and Dominic Sellitto, clinical assistant professor of management science and systems in the UB School of Management, will serve as co-principal investigators on the research.
NEWS
We’re hiring in Buffalo and Chicago
Positions are available in the Snell laboratory for a research technician in Buffalo New York. Click here for details.
We offer an excellent benefits package and a welcoming environment that embraces diversity in people as well as the skills they bring to us
NEWS
HWI Scientist Daniel Gewirth receives NIH Grant Award
Hauptman-Woodward Medical Research Institute Investigator Daniel Gewirth, PhD, has recently been awarded a four-year, $1.6 million grant from the National Institute of General Medical Sciences (NIGMS) of the The National Institutes of Health.
NEWS
HWI to join UB, strengthening medical science research and education in WNY
The move will bolster health, well-being and innovation in Buffalo Niagara and beyond
BUFFALO, N.Y. – Hauptman-Woodward Medical Research Institute will join the University at Buffalo, a move designed to strengthen the two organizations’ joint mission to advance medical science research and education in Western New York and beyond.
Read the full press release by clicking here
NEWS
Dr. Bowman Elected as New Fellow of the American Crystallographic Association
Congratulations to Sarah EJ Bowman for being elected as a new Fellow of the American Crystallographic Association – the Structural Science Society.
The ACA Fellows program serves to recognize a wealth of knowledge, experience and passion for structural science. The Fellows program celebrates the excellence of members of the ACA and promotes their recognition worldwide. ACA Fellows serve as scientific ambassadors to the broader scientific community and the general public to advance science education, research, knowledge, interaction, and collaboration.
RESEARCH
HWI Scientists Published in in Cell Press Cell Reports Physical Science
A team of Hauptman-Woodward Medical Research Institute scientists have a new publication in Cell Press Cell Reports Physical Science.
NEWS
Dr. Keefe Elected to Board of the AIP
Dr. Lisa J. Keefe has been elected by the Council of the American Crystallographic Association (ACA) to serve as a director on the Board of Directors of the American Institute of Physics (AIP).
Congratulations to Dr. Keefe on this appointment and on being a recognized leader in the community.
RESEARCH
Dr. Bowman Publishes in Acta Crystallographica C
Last November, Hauptman-Woodward Medical Research Institute scientist Sarah EJ Bowman, the director of the National Crystallization Center, was an invited speaker and participant in the Electron Diffraction Symposium and Workshop at the National Center for CryoEM Access and Training at the New York Structural Biology Center. The symposium resulted in a recently published paper in the journal Acta Crystallographica C, Structural Chemistry, entitled “Applying 3D ED/MicroED workflows toward the next frontiers“.
RESEARCH
Dr. Lynch Publishes in Biophysical Journal
Miranda Lynch at Hauptman-Woodward Medical Research Institute and a team led by collaborator Gregory Babbitt at Rochester Institute of Technology have just published a paper in Biophysical Journal describing ATOMDANCE.
Read the paper by visiting: https://authors.elsevier.com/c/1isgh1SPT7sJw
NEWS
Hauptman-Woodward Institute Scientist Participates in Study of Protein Folding Mechanisms
Dr. Daniel Gewirth, an Investigator at HWI, has participated in a study that examined the way in which proteins are activated in the human body. The collaborative study, published in the prestigious journal, Proceedings of the National Academy of Science, showed how helper proteins, called chaperones, collaborate with each other to achieve the folded state of their client proteins.
Read the full paper by clicking here.
RESEARCH
Dr. Paz publishes in Nature Communications
HWI scientist Dr. Aviv Paz was part of a team that published a paper entitled “Membrane potential accelerates sugar uptake by stabilizing the outward-facing conformation of the Na/glucose symporter vSGLT” in the journal Nature Communications. This work with scientists at the University of California Los Angeles and San Francisco has broad implications for transporting numerous chemicals in the body and managing life-threatening conditions like diabetes, heart failure, and kidney failure.
RESEARCH
Dr. Lynch is fighting drug resistance in HIV/AIDS
Around the world, HIV/AIDS continues to be a major health problem. Several treatment regimens have dramatically reduced HIV-related illness and death. HIV-1 protease is one of the critical targets of these regimens. However, this drug target is prone to the development of treatment resistance. HWI scientist Dr. Miranda Lynch and collaborators at the Rochester Institute of Technology recently published this research in Biophysics Reports in a paper entitled Evolution of drug resistance drives destabilization of flap region dynamics in HIV-1 protease.
NEWS
Dr. Snell joins the IUCr Book Series Committee
Dr. Edward Snell, Chief Scientific Officer at Hauptman-Woodward Medical Research Institute (HWI), has been appointed to the International Union of Crystallography (IUCr) Committee as a member of the Book Series Committee. The Committee recommends new book publications to the IUCr Executive Committee and the Delegates of Oxford University Press. Recommended publications are IUCr monographs, which are in-depth expositions of specialized topics in crystallography, crystallography texts providing standardized methods and approaches, and related books.
News
The Institute is home to the National Crystallization Center
This Five-year award from NIH brings prestige, jobs, investment to Western New York and recognizes almost two decades of our developments in this area. The National Crystallization Center provides access to state-of-the-art robotic instrumentation, advanced imaging technologies, and expertise in crystallization to the scientific community supporting both academia and industry.
The Center is actively involved in the fight against COVID-19.