The Crystallization Center at HWI
A paper selected for the Journal cover celebrating 20 years of crystal hits: progress and promise in ultrahigh-throughput crystallization screening by Miranda L. Lynch, M. Elizabeth Snell, Stephen A. Potter, Edward H. Snell, and Sarah E. J. Bowman.
Dr. Sarah EJ Bowman and the National Crystallization Center help address the challenge of finding new antimicrobials
HWI has been involved in a large collaborative project resulting in a paper published in Nature Microbiology.
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We offer an excellent benefits package and a welcoming environment that embraces diversity in people as well as the skills they bring to us
Dr. Sarah EJ Bowman and Dr. Miranda L Lynch have received a new $1.57M grant from the National Institutes of Health.
A $1.57M grant from the National Institutes of Health to supports research on detecting and handling small crystals for cutting edge structural biology. Structural characterization of biomolecules important in human health and disease is crucial to understanding how these molecules function, as well as to designing therapeutics. Structural methods that make use of vanishingly small crystals have the potential to revolutionize how we obtain highly detailed structural ‘snapshots’ of biomolecules.
Dr. Monterio was elected as vice-chair of the Users’ Exectutive Committe for NSLS-II
Dr. Diana Monteiro was elected as vice-chair of the Users’ Executive Committee for NSLS-II, one of the newest and most advanced synchrotrons in the world. Synchrotrons are particle accelerators that produce the powerful X-rays needed for structural biology research.
Drs. Edward Snell and Stephan Ginell elected as American Crystallographic Association Fellows
Drs. Snell and Ginell are proud to be joining the ACA Fellow ranks, which include three Nobel laureates.
HWI staff in Chicago help Pfizer create an effective COVID-19 treatment
Our team at the Advanced Photon Source have helped Pfizer create a COVID-19 treatment. The new drug candidate, Paxlovid, significantly reduced hospitalization and death in adult patients, according to Pfizer, and will be submitted for an emergency use authorization in the United States.
The Institute is home to the National Crystallization Center
This Five-year award from NIH brings prestige, jobs, investment to Western New York and recognizes almost two decades of our developments in this area. The National Crystallization Center provides access to state-of-the-art robotic instrumentation, advanced imaging technologies, and expertise in crystallization to the scientific community supporting both academia and industry.
The Center is actively involved in the fight against COVID-19.
Take a closer look at HWI’s world-class Cryo-EM center.
Dr. Sarah Bowman on one way HWI is working to combat COVID-19.
Part of a series from researchers across the Northeast United States on the scientific efforts that are underway to address the current pandemic.
HWI Young Professionals Program
Structural biology at the center of COVID-19 scientific efforts
Synergy between X-ray crystallography, cryoelectron microscopy and computational methods has led to critical advances indispensable to developing treatments for infection and vaccines for prevention.
Accurate identification of metals in proteins.
Many proteins contain metals. Accurate identification of these is a prerequisite to understanding the biological mechanism and curing disease. An international team co-led by Dr. Snell developed a sensitive method to accurately determine both the metal type and position using very small volumes of protein.
Helping others crystallize proteins.
Drs. Sarah Bowman & Miranda Lynch and intern Max Dudek have their work featured on the cover of the journal.
Dr. Diana Monteiro is working with an international collaboration of scientists from the University of Buffalo, Germany, and France to develop new tools allowing us and others to understand how life works.
Helping cure disease.
Information on the dynamics of a system associated with inflammation, autoimmune disorders, fibrosis, cancer, and cataracts is revealed.