The COVID-19 pandemic has impacted almost every aspect of our lives in the past year and continues to do so. In March, at the one-year mark of the World Health Organization declaration that COVID-19 is a pandemic, researchers at HWI – Dr. Miranda Lynch, Dr. Edward Snell and Dr. Sarah Bowman – delved into the role structural biology has played in the fight against COVID-19.

They have published a new perspective in IUCrJ highlighting the amazing work done by the structural biology community on SARS-CoV-2, the virus that causes COVID-19.  Synergy between X-ray crystallography, cryoelectron microscopy and computational methods has led to critical advances indispensable to developing treatments for infection and vaccines for prevention.

The fight is ongoing; unsolved SARS-CoV-2 protein structures and emerging variants remain that require the continued attention and skills of the structural biology community.

Examination of publicly available SARS-CoV-2 structures introduces us to the power of structural biology and the impact it has had on the global fight against COVID-19.