by Sarah Bowman | Sep 30, 2020 | Crystallization-Center
Summer intern Ethan Hollerman won a Student Poster Prize at the 2020 LCLS/SSRL Users’ Meeting for his work on implementing the MARCO algorithm into a new GUI! MARCO POLO is a multi-platform open-source Python-based graphical user interface that has been...
by Sarah Bowman | Aug 9, 2020 | Crystallization-Center
Crystal structures of AztD from pathogenic bacteria by Crystallization Center user Professor Erik Yukl and team reveal mechanistic insights into zinc transfer! Initial crystal hits were obtained in the Crystallization Center and were optimized by the investigators...
by Sarah Bowman | Jun 24, 2020 | Crystallization-Center
The COVID-19 disease caused by the SARS-CoV-2 coronavirus has become a pandemic health crisis. An attractive target for antiviral inhibitors is the main protease 3CL Mpro due to its essential role in processing the polyproteins translated from viral RNA. The...
by Sarah Bowman | Dec 20, 2019 | Crystallization-Center
Transforming growth factor -1 (TGF-1) is a secreted signaling protein that directs many cellular processes and is an attractive target for the treatment of several diseases. This study looks at the regulatory mechanism of TGF-1 and is of fundamental importance for...
by Sarah Bowman | Oct 12, 2018 | Crystallization-Center
Mutations in ABC subfamily C member 6 (ABCC6) transporter are associated with pseudoxanthoma elasticum, a disease resulting in ectopic mineralization and affecting multiple tissues. The Thibodeau Group recent paper explores these mutations. Crystallization screening...
