Transforming growth factor -1 (TGF-1) is a secreted signaling protein that directs many cellular processes and is an attractive target for the treatment of several diseases. This study looks at the regulatory mechanism of TGF-1 and is of fundamental importance for therapeutic development. Initial crystal hits were obtained from the Crystallization Center and X-ray data were collected on the IMCA beamline at the Advanced Photon Source. The study was published in a paper entitled “Structural insights into conformational switching in latency-associated peptide between transforming growth factor β-1 bound and unbound states” in IUCrJ with PDB ID 6P7J (Stachowski, TR, et al. IUCrJ 2020; 7, 238-252). A combination of crystallographic and small-angle X-ray scattering approaches was used with the solution data deposited as SASDFD2.