Crystallization Cocktails

Crystallization is carried out using 1,536 different chemical cocktails. These are grouped by generation. Each generation represents successive improvements in capability and performance. With the exception of generation 13 and 13a, they are updated on a yearly basis. In the table below the cocktails are detailed by most recent first with the plate number (the code associated with each sample submitted) and the dates that the cocktails were in use. A download option links to an Excel file containing chemical details of the cocktail. A historical perspective on the incorporation of cocktails is available in a paper by the Center entitled “Crystallization screening: the influence of history on current practice“.

Soluble sample cocktails are shown first followed by those used for membrane-based sample screening. Soluble sample experiments are donated by an ‘X’ number, while membrane samples by an ‘M’ number for sample identification.

National Crystallization Center High-Throughput Cocktails

Cocktail GenerationPlate NumbersDates usedDownload
 Soluble (standard) sample screens
20*X16101 -09/21/2021 - currentdownload
19*X15790 - X1610003/17/2020 - 9/20/2021download
18*X15568 - X1578910/23/2018 - 3/16/2020download
17*X15299 - X1556707/18/2017 - 10/22/2018download
16 X14970 - X1529811/17/2015 - 06/28/2017download
15X14714 - X1496911/12/2014 - 11/6/2015download
14X14246 - X1471310/16/2013 - 11/05/2014download
13aX14065 - X1424506/11/2013 - 10/11/2013download
13X13660 - X1406410/16/2012 - 06/07/2013download
12X12997 - X1365909/13/2011 - 10/12/2012download
11X12343 - X1299610/19/2010 - 09/01/2011download
*Note .xls files for generation 17-20 reflect the physical location in the 1,536 well in the `well position' column
Membrane sample screens
9M908 -04/04/2022 - currentdownload
8M807 - M90711/30/2015 - 04/03/2022download