by Edward Snell | Jan 8, 2020 | Snell-lab
Metalloproteins play a key role in the progression of many diseases. Using ion beam analysis through particle-induced X-ray emission (PIXE) and anomalous X-ray analysis we have quantitatively identified the metal atoms in 30 previously structurally...
by Edward Snell | Jul 1, 2019 | Snell-lab
Xylose isomerase (XI) is an industrially important metalloprotein studied for decades. Its reaction mechanism has been postulated to involve the movement of the catalytic metal cofactor to several different conformations. Here, a dose-dependent approach was used to...
by Edward Snell | Apr 14, 2019 | Snell-lab
Dissociation of transforming growth factor beta-1 (TGF-β1) from the inhibitory protein latency-associated peptide (LAP) can occur from low doses of X-ray irradiation of the LAP–TGF-β1 complex, resulting in the activation of TGF-β1 and can have health-related...
by Edward Snell | Sep 19, 2018 | Snell-lab
A book entitled Biological Small Angle Scattering: Theory and Practice, by Eaton Lattman, Thomas Grant, and Edward Snell, is part of an International Union of Crystallography series that provides in-depth knowledge of specialized topics. The technique of small-angle...
