by Edward Snell | Jan 20, 2022 | Snell-lab
In 2005 we looked at the status of growing crystals in space, four years after the final flight of the Space Shuttle Orbiter, and five years before the first commercial flight to the International Space Station. Since then, there have been developments in access to...
by Edward Snell | Nov 1, 2021 | HWI News, Snell-lab
Studying radiation damage in biological systems – New tools and new knowledge X-ray-based techniques are a powerful tool in structural biology but the radiation-induced chemistry that results can be detrimental and may mask an accurate structural understanding....
by Jeff Surdej | May 4, 2021 | HWI News, Snell-lab
The COVID-19 pandemic has impacted almost every aspect of our lives in the past year and continues to do so. In March, at the one-year mark of the World Health Organization declaration that COVID-19 is a pandemic, researchers at HWI – Drs. Miranda Lynch, Edward Snell...
by Edward Snell | Nov 17, 2020 | HWI News, Snell-lab
A significant problem in biological X-ray crystallography is the radiation chemistry caused by the incident X-ray beam. This produces both global and site-specific damage. Site-specific damage can misdirect the biological interpretation of the structural models...
by Edward Snell | Jul 31, 2020 | Snell-lab
Dr. Timothy Stachowski, defended his Ph.D. thesis entitled “Towards Understanding the Structural Impact from Therapeutic Radiation Doses from Mechanisms in Engineered Systems to to TGF-β1”. Dr. Stachowski was a Biophysics Ph.D. student in the Snell...
by Edward Snell | Mar 1, 2020 | Snell-lab
Transforming growth factor -1 (TGF-1) is a secreted signaling protein that directs many cellular processes and is an attractive target for the treatment of several diseases. This study looks at the regulatory mechanism of TGF-1 and is of fundamental importance for...
