The Bowman Lab at Hauptman-Woodward Medical Research Institute (HWI) seeks a postdoctoral associate to work on a funded NIH R01 Technology Development grant. We are looking for someone who is excited to use and develop structural biology methods for small protein crystals. This collaborative project involves developing nano- and microcrystal growth methods, crystal sample imaging and handling experiments, as well as data collection and structural solutions. This is an ideal position for a creative scientist who is passionate about structural biology and wants to work in an exciting and collaborative group.

The successful candidate will have an opportunity to use a number of structural biology methods, including synchrotron X-ray crystallography and microcrystal electron diffraction, with options to also engage with X-ray Free Electron Laser experiments and single particle CryoEM experiments. The position offers the opportunity to work closely with teams at the National High-Throughput Crystallization (HTX) Center and the CryoEM Center, both located at HWI in Buffalo, NY.


    • PhD in a relevant field
    • Ability to design and perform laboratory experiments with deep attention to detail and excellent organizational skills
    • Strong problem-solving skills
    • Ability to work independently and collaboratively in a fast-paced research environment
    • Excellent written and oral communication skills


    • Experience in protein structure determination
    • Strong computational skills
    • Knowledge of protein biochemistry, recombinant protein expression, and/or other molecular biology methods

We welcome all applicants who have a passion for structural biology research and an interest in technology development.


Please send a cover letter describing your interest in the position and your career goals, as well as a current CV and contact information (name, phone, and email) for three references to Sarah Bowman, PhD, at


HWI is a thriving site for structural biology research, with outstanding facilities and regular synchrotron access. It houses the National High-Throughput Crystallization Center, a NIH NIGMS National Resource that Dr. Bowman directs, as well as the recently opened HWI CryoEM Center in Buffalo, NY. HWI also manages the IMCA-CAT beamline 17-ID at the Advanced Photon Source at Argonne National Laboratory in Lemont, IL.

The postdoctoral associate position will be based in Buffalo, NY. Application review will begin immediately, and the position will remain open until filled. The compensation level for this full-time position will be competitive and commensurate with the candidate’s qualifications. HWI provides a generous benefits package. HWI is an equal opportunity employer and is committed to creating a diverse and inclusive environment for all employees.


HWI, as an equal opportunity employer, extends employment opportunities to qualified applicants and employees on a non-discriminatory basis without regard to race, color, sex, creed, age, religion, national origin, marital status, veteran status, sexual orientation, genetic predisposition, carrier status, or disability that would prevent the performance of the essential requirements of the job with or without a reasonable accommodation in compliance with the appropriate New York State and Federal laws, or any other legally protected characteristics. This policy applies to all conditions and terms of employment.