The focus of the UB/HWI Structural Biology Department is biological form and function at the level of the three-dimensional atomic architecture of biological macromolecules and macromolecular assemblies.  The Department’s program of graduate studies provides thorough training in the principles and practice of the main methodologies of structural molecular biology, namely: protein expression, purification, and crystallization; X-ray diffraction crystallography; small angle X-ray scattering; and computational structural modeling.

The core faculty of the Structural Biology Department is comprised of scientists from the Hauptman-Woodward Medical Research Institute, Inc., an internationally renowned biocrystallographic research center.  The Institute and Department are housed in a beautiful new building on the Buffalo-Niagara Medical Campus, adjacent to the new building complex that houses the UB Center of Excellence in Bioinformatics and Life Sciences and the Roswell Park Cancer Institute Centers for Genetics and Pharmacology.

One track of the Structural Biology Ph.D program includes the first-year required course work for the Ph.D. program in Biomedical Sciences.  In their second year, students choose a thesis or dissertation research topic and faculty advisor, and they commence their degree research.  For admission to degree candidacy, students are required to present and defend orally a written proposal for their research project.

The Ph.D. dissertation research must represent on original investigation designed to contribute to new knowledge and understanding of biomolecular form and function or new methodology for research in structural biology.  It is expected that the research will normally lead to publication in prominent refereed journals of one or more research papers of which the student is the principal author.

For more information, contact the Department Chair:

Michael Malkowski, Ph.D.